Oxidative Stress and DiseasesW. Jean Dodds, DVM2019-04-13T20:24:25+00:00
Oxidative Stress and Diseases
Oxygen-derived free radicals always accompany mitochondrial energy production
Creating free radicals causes cell toxicity
Even in healthy state, ~ 25% of oxygen intake forms free radicals
In unhealthy states, up to 75% of oxygen becomes free radicals
Common causes of oxidative stress: toxemia, infections, hypoxia-ischemia, hyperglycemia, xenobiotics (drug metabolism), hyperlipidemias, hyperproteinemias, cancers, phagocytic and immune reactions, and high metabolic rates
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